Abstract: The concept of Pranavaha Srotas and Pranavayu represents the Ayurvedic understanding of respiratory physiology, life-sustaining processes, and systemic regulation. In Ayurveda, Prana is considered a fundamental life force responsible for respiration, sensory perception, mental activity, and maintenance of vital functions. Pranavaha Srotas, described as the channel system responsible for carrying Prana, is closely associated with the functioning of the respiratory system and the regulation of physiological activities. Modern physiology recognizes respiration as a complex process involving pulmonary ventilation, gas exchange, neural regulation, and oxygen delivery, which together maintain cellular metabolism and homeostasis. This literary review critically analyzes the relationship between Pranavaha Srotas and the functions attributed to Pranavayu by correlating classical Ayurvedic descriptions with contemporary physiological concepts. Classical texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya were reviewed along with modern scientific literature from PubMed, Scopus, and Web of Science. The review suggests that Pranavayu functions such as inhalation (Shwasa), speech (Vak Pravritti), sensory coordination, mental activity, and maintenance of vital energy can be interpreted through the integrated functions of respiratory, nervous, and cardiovascular systems. Disturbance of Pranavaha Srotas may correlate with respiratory disorders, impaired oxygenation, and autonomic dysfunction. Understanding this association may provide a broader integrative framework for respiratory physiology and disease management.

Keywords: Pranavaha Srotas, Pranavayu, Ayurveda, respiratory physiology, Srotas, Prana, literary review

Abstract: Neurodevelopmental disorders represent a group of conditions arising from disturbances in brain development and function during early childhood. Increasing prevalence of developmental delays, autism spectrum disorder, attention- deficit/hyperactivity disorder, intellectual disability, speech disorders, and learning difficulties has created a significant global health burden. Modern neuroscience attributes these disorders to complex interactions between genetic factors, prenatal influences, environmental exposures, neuroinflammation, and altered neural connectivity. Ayurveda, the ancient science of life, provides a comprehensive pediatric perspective through the principles of Kaumarbhritya, Bala, Manas, Indriya, and Bala Graha. The concept of Bala Graha describes subtle pathological influences affecting children, particularly involving cognition, behavior, sensory functions, and developmental processes. This review critically evaluates the relationship between classical Ayurvedic descriptions of Bala Graha and contemporary concepts of neurodevelopmental disorders. Classical texts including Kashyapa Samhita, Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya were analyzed along with modern scientific literature from PubMed, Scopus, and Web of Science. The review suggests that disturbances described in Ayurveda as impairment of ManovahaSrotas, Vata Dosha, Ojas, and Medha may be conceptually correlated with neurodevelopmental dysfunction. Ayurvedic approaches including Snehana, Swedana, Nasya, Basti, Medhya Rasayana, and supportive lifestyle measures may provide a holistic framework for improving neurological development. Further clinical research integrating Ayurvedic concepts with modern neurodevelopmental assessment tools is required.

Keywords: Developmental disorders, Bala Graha, Ayurveda, neurodevelopment, Medhya Rasayana, Kaumarbhritya, child health

Abstract: The rapid expansion of digital technology has transformed human lifestyle, communication, education, and occupational patterns. Excessive use of smartphones, computers, tablets, and digital media has introduced a new set of health concerns collectively associated with a sedentary digital lifestyle. Increased screen exposure, especially during evening and nighttime hours, has been linked with sleep disturbances, reduced attention span, emotional dysregulation, anxiety, visual strain, and altered cognitive functions. Modern research highlights the role of blue light exposure, circadian rhythm disruption, psychological stimulation, and reduced physical activity in producing these effects. Ayurveda emphasizes the importance of balanced lifestyle through the concepts of Dinacharya, Nidra, Manas, and regulation of sensory activities (Indriya Nigraha). Excessive and inappropriate engagement with sensory objects is described as a form of Asatmya Indriyartha Samyoga and Prajnaparadha, which may disturb mental and physiological equilibrium. This review critically analyzes the impact of digital lifestyle on health through both modern and Ayurvedic perspectives. Classical Ayurvedic texts and recent scientific literature from PubMed, Scopus, Web of Science, and Google Scholar were reviewed. The analysis suggests that prolonged digital exposure may be correlated with disturbance of Vata Dosha, impairment of Manovaha Srotas, disturbed Nidra, and reduced mental stability. Ayurvedic approaches including lifestyle regulation, Dinacharya, yoga, meditation, Nasya, and Medhya Rasayana may provide preventive strategies for maintaining psychological and physiological balance in the digital era.

Keywords: Digital lifestyle, screen time, Nidra, Manas, Ayurveda, mental health, circadian rhythm

Abstract: Air pollution has become one of the most significant environmental determinants affecting human health. Continuous exposure to particulate matter, nitrogen oxides, sulfur dioxide, ozone, and chemical pollutants contributes to increasing incidence of upper respiratory tract disorders and ENT-related morbidity. The nasal cavity, paranasal sinuses, pharynx, and laryngeal structures act as the primary interface between inhaled pollutants and the human body, making them highly vulnerable to environmental insults. Modern research demonstrates that air pollutants induce mucosal irritation, oxidative stress, chronic inflammation, impaired mucociliary clearance, and immune dysregulation, leading to allergic rhinitis, chronic rhinosinusitis, pharyngitis, and headache disorders. Ayurveda describes similar pathological processes through the concepts of Pratishyaya, Shiro Roga, Kapha-Vata Dushti, and impairment of Pranavaha and Urdhvajatrugata Srotas. Classical texts explain that disturbance of normal Dosha function and accumulation of pathological factors result in obstruction of channels and manifestation of disease. This review critically evaluates the relationship between air pollution and ENT disorders from both modern and Ayurvedic perspectives. Classical Ayurvedic literature and recent scientific publications from PubMed, Scopus, and Web of Science were reviewed. The analysis suggests that pollutant-induced inflammation may be correlated with Kapha aggravation, Ama formation, and Srotodushti. Ayurvedic interventions including Nasya Karma, Kavala/Gandusha, dietary regulation, and Rasayana therapy may provide preventive and supportive approaches for pollution-associated ENT disorders. Further clinical and molecular research is required to validate integrative strategies.

Keywords: Air pollution, ENT disorders, Pratishyaya, Shiro Roga, Nasya, Ayurveda, respiratory health

Abstract: The rapid expansion of industrialization, urbanization, and modern lifestyle practices has resulted in continuous exposure to environmental pollutants including heavy metals, pesticides, air contaminants, chemical additives, and endocrine- disrupting compounds. Chronic low-dose exposure to these toxins contributes to oxidative stress, immune dysregulation, metabolic disorders, hormonal disturbances, and lifestyle-related diseases. Modern toxicology recognizes that persistent environmental toxins may accumulate within biological systems and produce delayed pathological manifestations. Ayurveda describes a similar phenomenon through the concept of Dushi Visha, referring to partially neutralized or accumulated toxins that remain in the body and produce disease after prolonged periods. Unlike acute poisoning, Dushi Visha manifests gradually due to interaction with Dosha, Dhatu, and Agni. This review critically analyzes the classical concept of Dushi Visha and its relevance in the contemporary era of environmental pollution and lifestyle disorders. Classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya were reviewed along with modern literature from PubMed, Scopus, and Web of Science. Evidence suggests that chronic exposure to pollutants may correlate with impaired metabolism, inflammation, oxidative damage, and reduced physiological resilience described in Ayurveda as Agni Dushti, Ama formation, and Ojas Kshaya. Ayurvedic interventions including Vishahara Chikitsa, Shodhana Karma, dietary regulation, and Rasayana therapy may offer preventive and restorative approaches. Integrative toxicological research combining modern environmental medicine with Ayurvedic principles may contribute to sustainable strategies for toxin-related disorders.

Keywords: Dushi Visha, environmental toxins, Ayurveda, pollution, Ama, Rasayana, lifestyle disorders

Abstract: Introduction: Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders affecting women of reproductive age. It is characterized by menstrual irregularities, hyperandrogenism, and polycystic ovarian morphology. In Ayurveda, it can be correlated with Artava-dushti involving Kapha-Meda vriddhi, Agnimandya, and Avarana of Apana Vata.

Keywords: COS, Virechana, Artava-dushti, Kapha- Meda, Shodhana

Abstract: Hypothyroidism is a common endocrine disorder characterized by inadequate thyroid hormone production, leading to reduced metabolic activity and multiple systemic manifestations. In Ayurveda, hypothyroidism can be understood in terms of Agnimandya, Kapha-Vata predominance, Rasavaha Srotodushti, and Medovaha Srotodushti. A 73-year-old female diagnosed with primary hypothyroidism presented with elevated serum thyroid stimulating hormone (TSH) while maintaining normal serum triiodothyronine (T3) and thyroxine (T4) levels. She underwent individualized Ayurvedic management comprising Deepana, Pachana, Kapha-Vata Shamana, Agni correction, Rasayana therapy, dietary regulation, and lifestyle modification.Following approximately 12 weeks of treatment, serum TSH decreased from 24 µIU/ml to 12.2 µIU/ml (approximately 49% reduction). Serum T3 improved from 0.84 ng/ml to 1.38 ng/ml, while serum T4 increased from 7.2 µg/dl to 8.67 µg/dl, remaining within the normal reference range. Conclusion: Individualized Ayurvedic management was associated with partial biochemical improvement in thyroid function. Although TSH remained above the normal reference range, serial laboratory findings suggested improvement. Larger controlled clinical studies are required to evaluate the effectiveness of Ayurvedic interventions in hypothyroidism.

Keywords: Hypothyroidism, Ayurveda, Agnimandya, TSH, Thyroid Function Test, Case Report

Abstract: Āyurvedic Saṃhitās are composed in concise Sanskrit language where the complete meaning of a statement is often hidden within grammatical structures and contextual application. To understand the deeper meaning of classical texts, Ācāryas have described various interpretative methodologies known as Tantrayukti. Tantrayukti acts as a tool for systematic understanding, compilation and interpretation of scientific literature. Knowledge of Sanskrit grammar, especially Pratyaya (suffixes) and Avyaya (indeclinables), plays an important role in identifying the intended meaning of textual statements. [1,2]

Keywords: Tantrayukti, Pratyaya, Avyaya, Caraka Saṃhitā, Sanskrit Grammar, Saṃhitā Interpretation

Abstract: Shift Work Sleep Disorder (SWSD) is a circadian rhythm sleep disorder commonly observed among individuals engaged in night shifts, rotating duties, and irregular work schedules. Chronic disruption of the sleep–wake cycle leads to impaired sleep quality, fatigue, metabolic disturbances, cognitive dysfunction, cardiovascular risk, and psychological stress. Modern management strategies primarily focus on sleep hygiene, pharmacotherapy, melatonin supplementation, and behavioral interventions; however, long-term outcomes remain inconsistent. Ayurveda describes sleep (Nidra) as one of the three fundamental pillars (Trayopastambha) essential for physiological equilibrium and mental health. Disturbance of natural circadian rhythms due to inappropriate lifestyle and nocturnal awakening (Ratri Jagarana) is considered a major cause of Vata aggravation, Manodosha imbalance, and impaired tissue restoration. The present randomized controlled clinical study evaluated the physiological impact of SWSD and analyzed sleep quality using Ayurvedic principles. Sixty participants with clinically diagnosed SWSD were randomized into trial and control groups. The trial group received Ayurvedic interventions including Nidrajanana Ahara-Vihara, Brahmi Churna, Ashwagandha Churna, and sleep hygiene counseling based on Ayurvedic principles, whereas the control group received conventional sleep hygiene advice alone. Assessment was performed using Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), perceived stress scale, heart rate variability, and serum cortisol levels. The Ayurvedic intervention group demonstrated statistically significant improvement in sleep quality, daytime alertness, stress scores, and autonomic balance. The study suggests that ancient Ayurvedic principles may provide an effective holistic approach in the management of SWSD and reshtoration of circadian harmony.

Keywords: Shift Work Sleep Disorder, Nidra, circadian rhythm, Ayurveda, sleep quality, Ratri Jagarana, randomized controlled trial

Abstract: Chronic dermatological disorders such as acne vulgaris, psoriasis, eczema (atopic dermatitis), and chronic urticaria are multifactorial conditions driven by inflammation, immune dysregulation, oxidative stress, microbial dysbiosis, and environmental triggers. Conventional treatments, including topical corticosteroids, systemic retinoids, biologics, and antibiotics, often provide symptomatic relief but are limited by adverse effects (e.g., skin atrophy, antibiotic resistance, and metabolic disturbances), high recurrence rates, and poor long-term tolerability. Herbal medicines, particularly polyherbal formulations from Ayurveda, are increasingly investigated as adjunctive or alternative options due to their multi-target mechanisms and favorable safety profiles. Vishaghna Mahakashaya, a classical group of ten medicinal plants described in Charaka Samhita (Sutrasthana 4.16), is traditionally indicated for antitoxic effect (vishaghna), anti-inflammatory, and skin-purifying actions. This review critically evaluates the available clinical evidence (2010–2025) and pharmacological mechanisms of Vishaghna Mahakashaya and its constituent herbs in chronic dermatological conditions. Databases searched included PubMed, Scopus, Google Scholar, and AYUSH Research Portal. Included were human clinical or observational studies and pharmacological evaluations relevant to skin disorders. Evidence, though predominantly preclinical and preliminary clinical, demonstrates reductions in inflammatory lesions, pruritus, erythema, and oxidative stress markers. Constituent herbs exhibit cytokine inhibition (TNF-α, IL-6), NF-κB suppression, mast-cell stabilization, antioxidant activity, and antimicrobial effects against skin pathogens. Synergistic polyherbal action aligns with the pathophysiology of chronic skin diseases. High- quality randomized controlled trials (RCTs) with standardized formulations are still required to establish efficacy, optimal dosing, and safety in integrative dermatology. Vishaghna Mahakashaya offers a rational, evidence-supported herbal strategy for managing these prevalent conditions.

Keywords: Ayurveda; Vishaghna Mahakashaya; dermatological disorders; acne vulgaris; psoriasis;eczema; chronic urticaria; immunomodulation; polyherbal formulation

Abstract: Emotional resilience refers to the capacity to adapt effectively to stress, adversity, and psychological challenges while maintaining mental well-being. The increasing prevalence of stress-related disorders, anxiety, depression, and burnout has intensified interest in preventive and holistic approaches to mental health. Ayurveda describes Achara Rasayana as a code of ideal behavioral conduct promoting mental equilibrium, longevity, and psychosocial well-being. Unlike pharmacological rejuvenation, Achara Rasayana emphasizes ethical living, disciplined behavior, emotional regulation, and social harmony as determinants of psychological resilience. This review critically evaluates the role of Achara Rasayana in enhancing emotional resilience through literary analysis and modern psychophysiological correlations. A structured literature review was conducted using classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya, along with modern databases such as PubMed, Scopus, and Web of Science. Evidence suggests that principles of Achara Rasayana including truthfulness, emotional restraint, compassion, meditation, self-control, and positive social behavior may influence neuroendocrine regulation, stress adaptation, and psychological stability. Contemporary psychological research supports the beneficial role of mindfulness, behavioral discipline, and prosocial conduct in resilience building. However, scientific evaluation of Achara Rasayana remainslimited due to lack of standardized assessment tools and interdisciplinary clinical studies. Integrating Ayurvedic behavioral concepts with modern psychological interventions may provide a comprehensive framework for preventive mental healthcare and resilience enhancement.

Keywords: Achara Rasayana, emotional resilience, Ayurveda, mental health, behavioral rejuvenation, stress adaptation, psychosocial well-being

Abstract: The oral microbiome plays a crucial role in maintaining oral and systemic health. Dysbiosis of oral microbial flora has been implicated in dental caries, gingivitis, periodontitis, halitosis, and several systemic disorders. Oil pulling, an ancient Ayurvedic oral hygiene practice known as Gandusha or Kavala, has gained increasing scientific interest as a complementary preventive strategy for maintaining oral microbial balance. Gandusha involves retaining medicated or non-medicated oils in the oral cavity for a specific duration to promote oral detoxification and tissue strengthening. This review critically evaluates the role of oil pulling in modulating the oral microbiome and improving oral health outcomes through analysis of classical Ayurvedic literature and contemporary scientific evidence. A structured literature review was conducted using classical Ayurvedic texts and modern databases including PubMed, Scopus, Web of Science, and Google Scholar. Evidence suggests that oil pulling with sesame oil, coconut oil, and medicated formulations may reduce oral bacterial load, plaque formation, gingival inflammation, and halitosis. Proposed mechanisms include mechanical cleansing, inhibition of bacterial adhesion, anti-inflammatory activity, and modulation of microbial ecology. Coconut oil demonstrates additional antimicrobial effects due to lauric acid content. Although several clinical studies report beneficial outcomes comparable to chlorhexidine mouthwash, methodological limitations such as small sample sizes and short study duration restrict definitive conclusions. Integrating Gandusha into preventive oral healthcare may provide a safe, economical, and holistic adjunctive approach. Further microbiome-based longitudinal studies are required to establish standardized protocols and mechanistic evidence.

Keywords: Gandusha, oil pulling, oral microbiome, Ayurveda, oral hygiene, periodontal disease, oral health

Abstract: Phaltrikadi Churna is an ancient Ayurvedic polyherbal powder described in Bhaishajya Ratnavali, under Madatyaya Chikitsa. This churna is predominantly used for the management of Panatyaya (hangover syndrome after alcohol consumption), Agni Deepana (activating digestive fire), and certain other disorders including Sangraha Grahani (constipation-predominant irritable bowel syndrome). Consisting of ingredients such as Triphala (Phaltrika), Trivrit, Devadaru, and different carminative plants and minerals, it has been used to correct dosha vitiation, especially Vata and Kapha dosha, with cleansing and balancing of digestion. This review highlights critical analysis of literature regarding the classical description, formulation, processing, pharmacological actions, and mechanism of Phaltrikadi Churna. The role of this formulation in treating the symptoms associated with alcohol disorder, enhancement of digestion, and stasis of digestive tract has been discussed.

Keywords: Phaltrikadi Churna, Bhaishajya Ratnavali, Madatyaya, Panatyaya, Agni Deepana, Sangraha Grahani

Abstract: Yonivyapad represents a broad spectrum of gynecological disorders described in Ayurveda under diseases affecting the female reproductive system. The Brihattrayi—Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya—provide detailed descriptions of the etiology, classification, symptomatology, and management of various Yonivyapad. Although these conditions were described in classical terminology, many correlate clinically with modern gynecological disorders such as pelvic inflammatory disease, vaginitis, menstrual abnormalities, infertility, and uterine prolapse. This review critically analyzes the descriptions of Yonivyapad in the Brihattrayi from literary and clinical perspectives and compares similarities and variations among classical texts. A structured literature review was conducted using Ayurvedic classics, commentaries, and modern databases including PubMed, Scopus, and Google Scholar. The review highlights that Charaka emphasizes systemic pathogenesis and internal medicine approaches, Sushruta focuses on surgical and anatomical aspects, whereas Ashtanga Hridaya presents concise therapeutic approaches integrating both traditions. Comparative analysis reveals differences in classification, nomenclature, and treatment principles, reflecting the evolving understanding of women’s health in classical Ayurveda. Modern gynecological correlations indicate significant conceptual overlap in pathophysiology and symptom presentation. However, the absence of standardized diagnostic criteria and limited clinical validation remain major challenges. This review underscores the relevance of classical Ayurvedic gynecology in contemporary integrative healthcare and identifies areas requiring further interdisciplinary research.

Keywords: Yonivyapad, Brihattrayi, Ayurveda gynecology, Stri Roga, women’s health, Ayurvedic classics, comparative review

Abstract: Diabetic neuropathy is one of the most common microvascular complications of diabetes mellitus, significantly affecting quality of life through pain, paresthesia, numbness, and sensory deficits. Conventional management primarily focuses on glycemic control and symptomatic relief; however, long-term outcomes remain suboptimal and are often associated with adverse drug effects. Ayurveda correlates diabetic neuropathy with Madhumehajanya Vatavyadhi, wherein aggravated Vata Dosha along with Dhatukshaya contributes to neurovascular dysfunction. Punarnava (Boerhavia diffusa), a well-known Ayurvedic drug possessing anti-inflammatory, antioxidant, neuroprotective, and Shothahara properties, may offer therapeutic benefits in diabetic neuropathy. The present randomized controlled clinical study evaluated the efficacy of Punarnava Churna in patients with diabetic neuropathy. Sixty diagnosed patients were randomly divided into two groups. Group A received Punarnava Churna along with standard diabetic care, while Group B received only conventional management. Clinical assessment was performed using Neuropathy Symptom Score (NSS), Visual Analog Scale (VAS), vibration perception threshold, and glycemic parameters before and after intervention. Patients receiving Punarnava Churna demonstrated significant improvement in burning sensation, tingling, numbness, pain scores, and sensory perception compared to the control group. The drug was well tolerated without significant adverse effects. The findings suggest that Punarnava Churna may serve as an effective adjuvant therapy in diabetic neuropathy through its Vatahara, anti-inflammatory, and neuroprotective actions. Further multicentric trials with larger sample sizes are necessary to validate these observations.

Keywords: Punarnava Churna, diabetic neuropathy, Madhumeha, Ayurveda, peripheral neuropathy, Vatavyadhi

Abstract: The management of localized inflammation (Shotha) and pain (Shoola) constitutes a significant portion of general medical
practice. While contemporary medicine largely relies on NSAIDs and topical analgesics, the Ayurvedic pharmacopeia
offers a range of transdermal applications known as Lepa. This review critically examines the formulation Panchakoladi
Lepa, a compound cited in the Charaka Samhita comprising five specific pungent herbs. The paper analyzes the rationale
behind this formulation, its putative mechanism of action regarding Kapha-Vata stagnation, and the clinical precautions
required due to its vesicant properties. We posit that Panchakola acts not merely as a counter-irritant, but as a localized
metabolic stimulant (Agni enhancer) capable of penetrating deep tissue barriers.

Abstract: Abhrak Bhasma is a traditional Ayurvedic medicine made from purified mica. Mica is known for its layered Structure and
is rich in various minerals like magnesium, potassium, and iron. It is valued for boosting energy, Enhancing immunity, and
promoting overall wellness. It is unique and important bhasma preparation used in Ayurvedic therapeutics. Present study
deal with pharmaceutical procedure like shodhana dhanyabharak nirman &Abhrak marana. Abhraka which is classified
under Maharasa by various Acharya is a substance capable of Pacifying all 3 doshas of the body and could rejenuvate the
body but only in its edible form and thus conversion of Abhraka to its edible form is done by the process of nirvapana
(heating and dipping) and this process of conversion Is considered as purification process. The preparation process involves
careful purification and heating. This Bhasma is believed to support respiratory health, improve digestion, and promote
overall wellness. It’soften used in Formulations for conditions like anemia and general weakness. However, it’s essential
to consult a qualified practitioner Before using it, as proper dosage and preparation are crucial for safety and efficacy. To
prepare the Bhasma, selective Metallic/mineral origin materials are exposed repeatedly to Puta, which is a traditional
method of Bhasma preparation.

Abstract: Seasonal allergies, commonly manifesting as allergic rhinitis, are highly prevalent immunological disorders characterized
by nasal congestion, sneezing, rhinorrhea, and itching triggered by environmental allergens. Despite the availability of
antihistamines, intranasal corticosteroids, and immunotherapy, recurrence and long-term dependency on medications
remain challenges. In Ayurveda, allergic rhinitis can be correlated with Vata-Kaphaja Pratishyaya, and Nasya Karma—
the administration of medicated substances through the nasal route—is advocated as a primary preventive and therapeutic
modality for diseases of the head and neck region. This review critically evaluates the role of Nasya Karma, particularly
Pratimarsha Nasya, in preventing seasonal allergies by integrating classical Ayurvedic concepts with modern
immunological mechanisms. A structured literature review was conducted using classical texts (Charaka Samhita,
Sushruta Samhita, Ashtanga Hridaya) and modern databases including PubMed, Scopus, and Web of Science. Evidence
suggests that Nasya may enhance mucosal immunity, improve mucociliary clearance, and reduce allergen sensitivity
through anti-inflammatory and barrier-protective effects. Commonly used formulations include Anu Taila and Shadbindu
Taila. Although preliminary studies and clinical observations indicate potential benefits, high-quality randomized
controlled trials are limited. While modern treatments provide effective symptomatic relief, Nasya Karma offers apreventive, holistic approach. Integrative strategies combining both modalities may improve long-term outcomes and
reduce recurrence, warranting further scientific investigation.

Abstract: Iron-deficiency anemia (IDA) continues to be a major public health challenge in India, primarily due to inadequate
dietary intake, chronic blood loss, and poor tolerance to conventional oral iron supplements, which often results
in low patient compliance. In parallel, peptic ulcer disease has shown an increasing prevalence owing to faulty
dietary habits, stress, and lifestyle-related factors, significantly impairing quality of life. In Ayurvedic literature,
conditions such as Panduroga (anemia), Annadrava Shoola (gastric ulcer), and Parinama Shoola (duodenal ulcer)
closely resemble iron-deficiency anemia and peptic ulcer disease respectively. Dhatri Lauha, a classical herbo-
mineral formulation described in Bhaishajya Ratnavali, has been traditionally employed in the management of these disorders; however, systematic scientific evaluation and standardization remain limited. The present study
aims to evaluate the clinical safety, therapeutic efficacy, and quality control parameters of Dhatri Lauha in patients
suffering from iron-deficiency anemia and peptic ulcer-related conditions. Clinical findings demonstrated
significant improvement in hemoglobin levels, iron indices, and gastrointestinal symptoms without the occurrence
of serious adverse events. Furthermore, physicochemical analysis and X-ray diffraction were utilized to establish
analytical fingerprinting and quality benchmarks. The study supports the potential of Dhatri Lauha as a safe,
effective, and economical Ayurvedic intervention with scope for integration into national health programs.

Abstract: Arśa (piles/hemorrhoids) is a common anorectal disorder described extensively in Ayurvedic
classics. Yogaratnakara recommends Tiladi Modaka as a therapeutic formulation for Arśa, yet systematic
academic evaluation integrating classical rationale and modern research design remains limited. Objective: To
critically review the classical basis, pharmacological rationale, and contemporary evidence for Tiladi Modaka in
Arśa, and to propose a clinical research methodology. Methods: Classical references from Yogaratnakara and
allied Ayurvedic texts were reviewed. Available modern pharmacological and clinical literature on Tiladi Modaka
and its constituent drugs was synthesized. A prospective randomized pilot clinical trial protocol is proposed,
including standard operating procedures (SOPs) for drug preparation and quality control. Results: Classical texts
indicate Tiladi Modaka as Arśaghna through doṣa-śamana, śothahara, raktastambhana, and vranaropaṇa actions.
Modern studies on individual constituents suggest anti-inflammatory, venotonic, wound-healing, antimicrobial,
and laxative effects. Hypothetical pilot data presentation demonstrates potential reductions in pain, bleeding,
discharge, and pile mass size.

Keywords: Arśa; Piles; Tiladi Modaka; Yogaratnakara; Ayurvedic pharmacology; Hemorrhoids; Integrative medicine.

Abstract: Timira is a classical Ayurvedic ocular disorder described under Drishtigata Rogas, characterized primarily by progressive
diminution of vision. Ancient texts delineate its pathogenesis based on Dosha vitiation affecting successive ocular
structures (Patalas), eventually leading to severe visual impairment if untreated. In modern ophthalmology, refractive
errors—including myopia, hypermetropia, and astigmatism—represent the most common causes of visual impairment
globally, particularly among children and young adults. This review aims to critically analyze the concept of Timira and
explore its possible correlation with refractive errors from a contemporary biomedical perspective. A structured literature
review was conducted using classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya) and
modern databases such as PubMed, Scopus, and Web of Science. The analysis suggests that early stages of Timira,
particularly involvement of the first and second Patalas, share clinical similarities with refractive errors, including blurred
vision, difficulty in distant or near vision, and visual distortion. However, Timira is a broader pathological entity
encompassing progressive degenerative changes, whereas refractive errors are primarily optical abnormalities. Ayurvedic management focuses on Dosha balancing, Rasayana therapy, and local ocular procedures such as Tarpana and Anjana,
while modern treatment relies on optical correction and refractive surgery. Although conceptual overlaps exist, direct
equivalence remains limited. Integrative research is necessary to validate these correlations and explore complementary
therapeutic strategies.

Keywords: Timira, refractive errors, myopia, hypermetropia, Ayurveda ophthalmology, Drishtigata Roga, integrative medicine

Abstract: Haemorrhoids are among the most prevalent anorectal disorders, characterized by symptomatic enlargement and distal
displacement of anal vascular cushions. Conventional management includes conservative therapy and minimally invasive
procedures such as rubber band ligation (RBL), which is widely regarded as the standard treatment for grade I–III internal
haemorrhoids. In Ayurveda, Arsha is described as a disease caused by vitiation of Doshas, and Kshara Karma—a parasurgical procedure involving the application of alkaline substances—is advocated as an effective treatment modality. This
review aims to critically compare Kshara Karma and RBL in terms of efficacy, safety, recurrence, procedural aspects, and
patient outcomes. A structured literature review was conducted using classical Ayurvedic texts (Charaka Samhita, Sushruta
Samhita, Ashtanga Hridaya) and modern databases including PubMed, Scopus, and Web of Science. Evidence suggests
that both modalities are effective for internal haemorrhoids; RBL offers simplicity and rapid symptom relief, whereas
Kshara Karma provides a more comprehensive approach with potential for lower recurrence due to its tissue-destructive
and healing-promoting properties. However, Kshara Karma may be associated with increased procedural discomfort and
requires technical expertise. While RBL is supported by robust clinical evidence, studies on Kshara Karma are limited and heterogeneous. Integrative evaluation indicates that both modalities have distinct advantages, and selection should be
individualized based on disease severity, patient preference, and available expertise.

Keywords: Haemorrhoids, Arsha, Kshara Karma, rubber band ligation, Ayurveda surgery, minimally invasive procedures, anorectal disorders

Abstract: Recurrent upper respiratory infections (URIs) constitute a significant clinical burden, particularly in pediatric populations,
leading to repeated morbidity, antibiotic use, and healthcare utilization. Conventional management primarily focuses on
symptomatic relief, prevention, and addressing underlying risk factors; however, recurrence remains a persistent challenge.
In Ayurveda, Pratimarsha Nasya, a form of daily nasal administration of medicated oils or ghee in small doses, is described
as a preventive and therapeutic modality for disorders involving the head and neck region. This review critically evaluates
the role of Pratimarsha Nasya in the prevention and management of recurrent URIs, correlating classical Ayurvedic
principles with modern concepts of mucosal immunity and respiratory defense mechanisms. A structured literature review
was conducted using classical texts (Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya) and modern databases
including PubMed, Scopus, and Web of Science. Evidence suggests that Pratimarsha Nasya may enhance local immunity,
improve mucociliary clearance, and maintain nasal mucosal integrity. Medicated oils such as Anu Taila and Shadbindu
Taila are traditionally indicated. Modern studies on nasal oil application indicate potential benefits in reducing pathogen
adherence and inflammation, although robust clinical trials are limited. While Ayurvedic descriptions emphasize daily
preventive use without significant adverse effects, contemporary evidence remains insufficient for definitive conclusions.
Integrative approaches combining Pratimarsha Nasya with standard preventive strategies may offer a promising avenue
for reducing URI recurrence, warranting further scientific validation

Keywords: Pratimarsha Nasya, recurrent upper respiratory infections, Ayurveda, mucosal immunity, nasal therapy, Anu Taila, integrative medicine

Abstract: Migraine is a prevalent neurovascular disorder causing significant disability worldwide. Limitations of
conventional pharmacotherapy, including adverse effects and recurrence, necessitate exploration of alternative therapies.
Virechana Karma, a therapeutic purgation procedure in Ayurveda, is traditionally indicated in Pitta-dominant disorders
such as Ardhavabhedaka (migraine).

Keywords: Virechan Karma, Migrane in Children, Shirorog, Ardhavabhedak, Suryavarta

Abstract: The Tridosha Siddhanta constitutes the foundational theoretical framework of Ayurveda, describing physiological and
pathological processes through the dynamic interplay of Vata, Pitta, and Kapha. Despite its central role in clinical
practice, its correlation with modern physiological principles remains a subject of ongoing debate. This review aims to
critically analyze the Tridosha Siddhanta in the context of contemporary biomedical understanding, exploring its
conceptual parallels, limitations, and translational relevance. A structured literature review was conducted using
PubMed, Scopus, Web of Science, and classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and
Ashtanga Hridaya. The findings suggest that Vata may be functionally correlated with neurophysiological processes and
movement regulation, Pitta with metabolic and enzymatic activities, and Kapha with structural integrity and anabolic
processes. However, these correlations remain largely interpretative and lack direct empirical validation. Modern
physiology, grounded in molecular and cellular mechanisms, provides precise quantification and experimental reproducibility, whereas the Tridosha framework offers a systemic, qualitative, and individualized approach. The review
highlights both conceptual overlaps and epistemological differences, emphasizing the need for integrative research
methodologies. Bridging traditional Ayurvedic principles with modern biomedical science could facilitate the
development of personalized and holistic healthcare models. Further interdisciplinary studies employing systems biology
and computational modelling are required to substantiate these correlations and enhance their clinical applicability.

Keywords: Tridosha Siddhanta, Ayurveda, Vata, Pitta, Kapha, modern physiology, integrative medicine

Abstract: Rasayana is a specialized branch of Ayurveda aimed at promoting longevity, immunity, intellect, and
tissue rejuvenation. The foundational exposition of rasayana is found in Charaka Samhita, where it is systematically
elaborated under Chikitsa Sthana (1). Subsequent classical texts such as Sushruta Samhita and Ashtanga Hridaya
expanded and modified its conceptual and therapeutic dimensions (2,3). However, a structured comparative analysis of
its evolution remains limited. Objective: To critically analyze the evolution of the rasayana concept from Charaka
Samhita to Ashtanga Hridaya, highlighting textual, philosophical, and therapeutic developments. Methods: A systematic
review was conducted following PRISMA 2020 guidelines (4). Primary classical texts were analyzed with chapter and
verse references. Secondary sources were retrieved from PubMed, Scopus, Google Scholar, and AYUSH Research Portal
up to December 2025. Comparative textual synthesis was performed. Results: The analysis demonstrates a conceptual
progression from primarily rejuvenative and longevity-focused therapy in Charaka (1) to surgical relevance in Sushruta
(2) and a more concise, clinically applicable framework in Ashtanga Hridaya (3). Expansion in classification,
indications, and practical formulations is evident. Conclusion: The rasayana concept evolved from a primarily
longevity-focused doctrine in Charaka to a clinically systematized and therapeutically integrated framework in Ashtanga
Hridaya, reflecting adaptive textual refinement across classical Ayurveda. Keywords: Rasayana, Charaka Samhita,
Ashtanga Hridaya, Rejuvenation, Immunomodulation, Ayurvedic pharmaceutics

Keywords: Rasayana, Charaka Samhita, Ashtanga Hridaya, Rejuvenation, Immunomodulation, Ayurvedic pharmaceutics

Abstract: Lifestyle disorders such as obesity, diabetes mellitus, hypertension, cardiovascular diseases, and metabolic syndrome
have emerged as major global health concerns. Sedentary habits, unhealthy dietary patterns, disturbed sleep, and
psychological stress contribute significantly to their pathogenesis. Ayurveda emphasizes preventive healthcare through
Dinacharya (daily regimen), a structured lifestyle framework described in classical texts including Charaka Samhita,
Sushruta Samhita, and Ashtanga Hridaya. Practices such as early rising, oral hygiene, oil pulling, exercise (vyayama),
massage (abhyanga), regulated diet, and proper sleep are designed to maintain physiological balance and prevent disease.
This review critically examines the role of Ayurvedic daily regimen in preventing lifestyle disorders, correlating classical
principles with modern biomedical evidence. The integration of Dinacharya into contemporary preventive medicine may
offer a cost-effective and holistic approach to global health challenges (1–4).

Keywords: Dinacharya, lifestyle disorders, prevention, Ayurveda, circadian rhythm, metabolic syndrome

Abstract: Jatharagni is the principal digestive and metabolic fire described in Ayurveda, governing transformation
of ingested food into nutritive essence (ahara rasa). Classical literature identifies agni as the determinant of health,
strength, complexion, immunity, and longevity (1). Contemporary biomedical science attributes systemic metabolism to
coordinated enzymatic, mitochondrial, and endocrine mechanisms. Despite conceptual parallels, systematic comparative
analysis remains limited.

Keywords: Jatharagni, Agni, Cellular metabolism, Oxidative phosphorylation, Insulin resistance, Ayurveda

Abstract: Marma Sharir describes 107 vital anatomical loci where trauma produces severe functional impairment or
mortality. Classical Ayurvedic literature attributes these sites to the confluence of mamsa, sira, snayu, asthi, and sandhi
structures (1). Contemporary anatomical investigations suggest that these correspond to major neurovascular complexes
(2,3). Objective: To systematically evaluate classical descriptions of marma and correlate them with modern neurovascular
anatomy.Methods:A systematic review was conducted following PRISMA 2020 guidelines (4). Databases including
PubMed, Scopus, Web of Science, Google Scholar, and AYUSH Research Portal were searched up to December 2025.
Classical Ayurvedic texts were reviewed for textual references. Studies correlating marma with anatomical neurovascular
structures were included. Results: Forty-eight studies met inclusion criteria. Strong correlations were observed between
Sira marma and arterial trunks (5,6), Snayu marma with peripheral nerve plexuses (7), and thoracic marma with cardiac
and autonomic plexuses (8,9). Conclusion: Classical marma descriptions show significant convergence with modern
neurovascular anatomy. Integrative anatomical mapping may enhance trauma assessment and surgical safety.

Keywords: Marma, Neurovascular structures, Sushruta Samhita, Surgical anatomy, Trauma, Integrative medicine

Abstract: Bhasma preparations constitute an important class of herbo-mineral formulations in Ayurveda and are extensively used
in Rasashastra therapeutics. Despite their clinical significance, concerns regarding safety, reproducibility, and quality
control have necessitated scientific standardization. Classical Ayurvedic texts describe elaborate procedures including
shodhana, marana, jarana, and amritikarana for detoxification and incineration of metals and minerals. However,
variations in raw materials, processing parameters, heating patterns, and equipment introduce variability in the final
product. Modern regulatory requirements demand validated protocols incorporating physicochemical, spectroscopic, and
toxicological evaluation. This review critically examines the need for standardization in bhasma preparation, classical
guidelines, modern analytical advancements, regulatory perspectives, and prevailing challenges. The integration of
traditional wisdom with contemporary scientific tools is essential to ensure safety, efficacy, and global acceptability of
Ayurvedic metallic formulations (1–4).

Keywords: Bhasma, Rasashastra, standardization, shodhana, marana, quality control, heavy metals

Abstract: Background: Krimi Roga (parasitic and worm infestations) is one of the most commonly
described pediatric disorders in classical Ayurvedic literature, particularly under Kaumarbhritya.
While modern public health interventions have reduced the burden of severe helminthic
infestations, changing environmental conditions, urbanization, altered dietary habits, antibiotic
exposure, and hygiene practices have significantly modified the epidemiology and clinical
presentation of pediatric parasitic diseases.
Objective: To provide a comprehensive narrative review of Krimi Roga in children by integrating
classical Ayurvedic concepts with contemporary epidemiological trends and pediatric health
perspectives.
Methods: A narrative review was conducted using authoritative Ayurvedic texts (Charaka
Samhita, Sushruta Samhita, Ashtanga Hridaya, Kashyapa Samhita) and modern biomedical
literature related to pediatric parasitic infections, gut health, nutrition, and immunity. Relevant
review articles, epidemiological reports, and clinical studies were thematically synthesized.
Results: Ayurveda describes Krimi Roga as a multifactorial disease arising from Agnimandya,
Ama formation, Kapha predominance, and unhygienic practices, particularly in children with
immature digestion. Modern epidemiology shows a shift from overt heavy infestations to chronic,
low-grade, recurrent infections with significant nutritional and immunological consequences.
Ayurvedic management emphasizes Apakarshana, Prakriti Vighata, Nidana Parivarjana, and
long-term preventive care.
Conclusion: The Ayurvedic framework of Krimi Roga remains highly relevant in the context of
changing pediatric epidemiology. Its holistic, digestion-centered, and preventive approach
complements modern deworming strategies and may reduce recurrence and long-term morbidity.

Keywords: Krimi Roga; Pediatric Parasitic Infections; Kaumarbhritya; Ayurveda; Intestinal Worms; Child Nutrition

Abstract: Background: Metabolic syndrome (MetS) represents a global public health challenge
characterized by central obesity, insulin resistance, dyslipidemia, and hypertension. Ayurveda
describes a group of disorders arising from over-nutrition and sedentary lifestyle under
Santarpanottha Vyadhi. Classical descriptions of Medoroga, Prameha, Sthaulya, and Hridroga
demonstrate striking conceptual parallels with MetS.
Objective: To critically reinterpret Santarpanottha Vyadhi in the context of metabolic syndrome
by synthesizing classical Ayurvedic literature with contemporary biomedical evidence.
Methods: A systematic review was conducted following PRISMA 2020 guidelines. Databases
searched included PubMed, Scopus, Web of Science, Google Scholar, and AYUSH Research
Portal up to December 2025. Classical Ayurvedic texts (Charaka Samhita, Sushruta Samhita,
Ashtanga Hridaya, and commentaries) were reviewed to extract
onceptual frameworks. Eligible experimental, clinical, and observational studies addressing
metabolic disorders from Ayurvedic or integrative perspectives were included.
Results: Out of 78 identified records, 52 studies met inclusion criteria. Classical texts describe
Santarpana, Agnimandya, Medodushti, Ama formation, and Srotorodha as core pathological
mechanisms—closely aligning with insulin resistance, chronic low-grade inflammation, adipokine
dysregulation, and endothelial dysfunction described in MetS. Clinical studies indicate that
Ayurvedic interventions targeting Langhana, Rukshana, Shodhana, and Medohara strategies
improve metabolic parameters.
Conclusion: Santarpanottha Vyadhi offers a comprehensive, systems-based explanatory model for
metabolic syndrome. Integrating Ayurvedic pathophysiology with modern metabolic science can
enhance preventive and therapeutic strategies.

Keywords: Santarpanottha Vyadhi; Metabolic Syndrome; Medoroga; Ayurveda; Insulin Resistance; Over-nutrition

Abstract: Background: Predictive and preventive healthcare has become a global priority due to the rising
burden of chronic non-communicable diseases. Modern medicine increasingly focuses on
identifying preclinical stages of disease using biomarkers and risk stratification tools. Ayurveda,
through the concept of Purvarupa, describes disease-specific prodromal features that appear
before complete disease manifestation, offering a valuable opportunity for early intervention.
Objective: To critically review the Ayurvedic concept of Purvarupa and explore its relevance as a
predictive marker in preventive healthcare by correlating classical descriptions with contemporary
biomedical understanding.
Methods: A narrative review was conducted using classical Ayurvedic texts including Charaka
Samhita, Sushruta Samhita, Ashtanga Hridaya, and their authoritative commentaries, along
with contemporary literature on prodromal states, predictive medicine, and disease prevention.
Conceptual synthesis was undertaken to establish correlations between Ayurvedic and modern
frameworks.
Results: Purvarupa represents an identifiable, reversible stage in disease evolution corresponding
to modern prodromal or preclinical phases. Evidence from metabolic, cardiovascular, and
neurological disorders supports the relevance of early symptom-based prediction. Ayurvedic
preventive measures applied during Purvarupa Avastha align with modern primary prevention
strategies.
Conclusion: Purvarupa constitutes a clinically significant predictive model with substantial scope
in preventive healthcare. Scientific validation and integrative application may strengthen early
diagnosis and disease prevention.

Keywords: Purvarupa; Predictive markers; Preventive healthcare; Shatkriyakala; Early diagnosis; Ayurveda

Abstract: Background: Chronic musculoskeletal and neurological disorders constitute a major global
health burden, leading to long-term disability, reduced quality of life, and escalating healthcare
costs. Conditions such as osteoarthritis, chronic low back pain, cervical spondylosis, stroke
sequelae, and neuropathies often demonstrate incomplete response to conventional therapies.
Ayurveda considers these disorders predominantly Vata-Vyadhi, wherein Basti therapy is
described as the principal and most effective intervention.
Objective: To critically evaluate classical Ayurvedic concepts and contemporary scientific
evidence regarding the role of Basti therapy in the management of chronic musculoskeletal and
neurological disorders.
Methods: A systematic review was conducted in accordance with PRISMA 2020 guidelines.
Electronic databases including PubMed, Scopus, Web of Science, Google Scholar, and
AYUSH Research Portal were searched up to December 2025. Classical Ayurvedic texts
(Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya) were reviewed for textual references. Clinical, experimental, and observational studies assessing Basti therapy in
chronic musculoskeletal and neurological conditions were included.
Results: Of 82 records identified, 46 studies met the inclusion criteria. Classical literature
establishes Basti as the prime therapy for Vata-Vyadhi, with systemic action mediated through
Pakvashaya. Modern studies demonstrate that various forms of Basti—including Niruha,
Anuvasana, and Yapana Basti—exhibit analgesic, anti-inflammatory, neuromodulatory, and
functional restorative effects in chronic disorders. However, heterogeneity in study design and
protocols persists.
Conclusion: Basti therapy represents a rational, system-level intervention for chronic
musculoskeletal and neurological disorders. Integrative clinical trials with standardized
methodologies are essential to strengthen evidence and facilitate broader clinical acceptance.

Keywords: Basti; Vata-Vyadhi; Musculoskeletal Disorders; Neurological Disorders; Panchakarma; Ayurveda

Abstract: Background: Pregnancy-induced hypertension (PIH) remains a leading cause of maternal and
perinatal morbidity and mortality worldwide, particularly in low- and middle-income countries.
Despite advances in obstetric care, preventive strategies with long-term safety and fetal
compatibility remain limited. Ayurveda emphasizes preventive antenatal care (Garbhini
Paricharya), wherein Rasayana therapy plays a pivotal role in maintaining maternal homeostasis
and preventing disease manifestation.
Objective: To critically review classical Ayurvedic concepts and contemporary scientific
evidence regarding the role of Rasayana in the prevention of pregnancy-induced hypertension.
Methods: A systematic review was conducted following PRISMA 2020 guidelines. Electronic
databases including PubMed, Scopus, Web of Science, Google Scholar, and AYUSH Research
Portal were searched from inception to December 2025. Classical Ayurvedic texts
(Brihattrayi and major Nighantus) were reviewed for conceptual correlations. Clinical,
experimental, and observational studies evaluating Rasayana drugs or formulations relevant to
PIH prevention were included.
Results: A total of 63 records were identified, of which 41 studies met inclusion criteria.
Classical literature describes Rasayana as promotive of Ojas, vascular integrity, and Tridosha
balance—pathophysiological domains relevant to PIH. Modern studies indicate that commonly
used Rasayana agents such as Ashwagandha, Shatavari, Amalaki, and Guduchi exhibit
antihypertensive, antioxidant, endothelial protective, and anti-inflammatory properties. However,
robust pregnancy-specific randomized controlled trials are limited.
Conclusion: Rasayana therapy demonstrates substantial theoretical and emerging scientific
potential in the prevention of PIH. Integrative, well-designed clinical trials are warranted to
establish safety, efficacy, and standardized antenatal protocols.

Keywords: Pregnancy-Induced Hypertension; Rasayana; Ayurveda; Antenatal Care; Oxidative Stress; Endothelial Dysfunction

Abstract: Background
Lifestyle disorders such as obesity, type 2 diabetes mellitus, dyslipidaemia, hypertension,
metabolic syndrome, and non-alcoholic fatty liver disease (NAFLD) represent a global health
burden driven by sedentary behaviour, unhealthy diet, chronic stress, and disrupted circadian
rhythms. Ayurveda conceptualizes these conditions under Santarpanajanya Vyadhi, Agnimandya,
Ama, Medodushti, and Srotorodha. Panchakarma, traditionally viewed as a detoxification therapy,
offers deeper systemic effects that extend beyond elimination of toxins to metabolic regulation and
functional reprogramming.
Objective
To critically review the role of Panchakarma in lifestyle disorders, emphasizing its mechanisms in
metabolic reprogramming, correction of doshik imbalance, restoration of agni, and long-term
disease modification.
Methods
A narrative conceptual review was conducted using classical Ayurvedic texts (Charaka,
Sushruta, Ashtanga Hridaya), commentaries, Panchakarma treatises, and contemporary
databases (PubMed, Google Scholar, DHARA, AYUSH Research Portal). Ayurvedic
pathophysiology was correlated with modern metabolic concepts.
Results
Panchakarma therapies like Vamana, Virechana, Basti, Nasya, and Raktamokshana
demonstrate multi-level actions including correction of insulin resistance, lipid metabolism
regulation, gut-microbiome modulation, inflammation reduction, hormonal balance, and
autonomic recalibration. Clinical and experimental studies indicate improvements in metabolic
parameters, body composition, inflammatory markers, and quality of life.
Conclusion
Panchakarma represents a comprehensive metabolic reprogramming strategy rather than mere
detoxification. When applied judiciously and individually, it offers sustainable benefits in
lifestyle disorders by addressing root-cause pathology, preventing disease progression, and
restoring physiological homeostasis. Integrative models combining Panchakarma with modern
care merit further exploration.

Keywords: Panchakarma, Lifestyle Disorders, Metabolic Syndrome, Ama, Agni, Medodushti, Insulin Resistance, Integrative Medicine, Ayurveda, Metabolic Reprogramming

Abstract: The exponential rise in mobile phones, computers, and digital screens has led to prolonged screen
exposure across all age groups. Excessive screen use is increasingly associated with ocular
complaints such as digital eye strain, dry eye disease, myopia progression, and ENT manifestations
including tinnitus, hearing fatigue, allergic rhinitis, sinusitis, and voice disorders. Ayurveda, with
its holistic understanding of sensory organ health (Indriya Swasthya), offers preventive and
therapeutic insights for managing screen-related disorders.

Keywords: Screen overuse, Digital eye strain, ENT disorders, Ayurveda, Netra roga, Karna roga, Nasya, Rasayana

Abstract: Background
Complex fistula-in-ano is a challenging anorectal condition characterized by multiple tracts, high
fistulas, recurrent disease, and proximity to sphincter muscles. Conventional surgical approaches
risk sphincter damage, incontinence, and recurrence. Kshara Sutra Therapy (KST), an
Ayurvedic minimally invasive technique using medicated setons, has been recognized for decades
as an effective option for fistula management.
Objective
To review the evidence base for Kshara Sutra therapy in complex fistula-in-ano, discuss technical
innovations, and contextualize its mechanism and outcomes within both Ayurvedic and modern
surgical frameworks.
Methods
A narrative review was conducted using databases including PubMed, Google Scholar,
DHARA, AYUSH Research Portal, and key surgical journals. Traditional Ayurvedic texts
(Sushruta Samhita, Ashtanga Hridaya) and recent clinical trials, case series, and systematic
reviews were analyzed.
Results
Kshara Sutra therapy demonstrates high healing and low recurrence rates in complex fistulae
when compared to conventional fistulotomy/fistulectomy, particularly in high anal fistulas and
recurrent cases. Innovations such as modified setons (Guggulu/Triphala coated), preoperative
imaging guidance, and improved postoperative care have enhanced outcomes. Mechanistic
evidence suggests gradual chemical cauterization, fibrosis, and drainage as critical components
of healing.
Conclusion
Kshara Sutra therapy is a viable, sphincter-preserving approach for complex fistula-in-ano with
robust clinical evidence. Integrative surgical practice incorporating Kshara Sutra may reduce
morbidity and recurrence. Future directions include standardization and multicenter RCTs.

Keywords: Kshara Sutra, Ano-rectal fistula, Complex fistula-in-ano, Ayurvedic surgery, Sphincter

Abstract: Background
Pediatric allergic disorders such as allergic rhinitis, bronchial asthma, atopic dermatitis, food
allergy, and urticaria are increasing globally, particularly in urban pediatric populations. These
disorders significantly affect growth, immunity, school attendance, and quality of life.
Conventional therapies mainly provide symptomatic relief and are associated with recurrence and
long-term adverse effects. Ayurveda offers preventive and therapeutic strategies through
regulation of Agni, correction of Dosha imbalance, immune modulation, and Rasayana therapy.
Objective
To review the increasing incidence of pediatric allergic disorders and critically analyze
Ayurvedic preventive and therapeutic approaches based on classical Kaumarbhritya principles
and contemporary evidence.
Methods
Classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya,
Kashyapa Samhita, and Nighantus were reviewed. A literature search was conducted using
PubMed, Google Scholar, DHARA, and AYUSH Research Portal. Conceptual correlation
between Ayurvedic pathogenesis and modern immunological mechanisms was performed.
Results
Pediatric allergic disorders correlate with Pratishyaya, Tamaka Shwasa, Vicharchika, Kotha,
and Udarda in Ayurveda. These conditions arise due to Kapha-Vata predominance, Mandagni,
Aama formation, and Rasavaha–Pranavaha srotodushti. Preventive measures such as Garbhini
Paricharya, Lehana, Dinacharya, Ritucharya, and Rasayana play a crucial role. Therapeutic
interventions including Shamana, selective Shodhana, and immune-modulatory herbs show
promising outcomes.
Conclusion
Ayurvedic preventive and therapeutic strategies offer a holistic, safe, and sustainable approach
for managing pediatric allergic disorders. Integration of Ayurveda with modern pediatrics may
reduce disease recurrence, drug dependence, and long-term complications.

Keywords: Pediatric allergy, Kaumarbhritya, Ayurveda, Pratishyaya, Tamaka Shwasa, Rasayana, immune modulation, allergic disorders

Abstract: Ayurveda offers a profound conceptual framework for heredity through the classical
principles of Beeja (germ cell), BeejaBhaga (sub-unit of germ cell), and BeejaBhaga
Avayava (microstructural components of the sub-unit). These doctrines reflect early
Indian insights into congenital abnormalities, inherited traits, and the role of parental
factors in shaping progeny. Modern genetics, epigenetics, and molecular biology provide
robust scientific evidence that parallels these Ayurvedic concepts, particularly regarding
chromosomal behavior, gene regulation, gamete integrity, environmental influences on
the genome, and transgenerational epigenetic inheritance. This review critically examines
classical Ayurvedic references and interprets them through the lens of contemporary
genetics, emphasizing areas of conceptual convergence. The study finds that Ayurvedic
heredity theory aligns with epigenetic modulation, DNA damage responses, genomic
imprinting, and gene expression pathways, revealing Ayurveda’s timeless scientific

Keywords: Beeja, BeejaBhaga, BeejaBhaga Avayava, Ayurgenomics, epigenetics

Abstract: Biotransformation represents the body's ability to convert endogenous and exogenous substances
into forms that can be metabolized, utilized, or eliminated. Ayurveda describes this process
through the concepts of Agni, Ama, and Srotas, with Shodhana (Panchakarma) therapies acting as
the primary means to restore metabolic balance. Modern research now recognizes the capacity of
detoxification therapies to regulate inflammatory biomarkers, enhance gut microbiome diversity,
and modify metabolic pathways. This review aims to correlate Ayurvedic principles of Shodhana
with contemporary biochemical mechanisms of biotransformation, highlighting Panchakarma’s
influence on detoxification, gut health, mitochondrial activity, hormonal balance, and systemic
homeostasis

Keywords: Panchakarma, Biotransformation, Shodhana, Agni, Ama, Detoxification, Gut Microbiome, Virechana, Vamana, Basti, Metabolic Reset.

Abstract: Sushruta, hailed as the father of surgery, described Trividha Shastra Karma—Chedana
(excision), Bhedana (incision), and Lekhana (scraping)—as the foundation of all operative
interventions. Modern surgery, particularly Minimally Invasive Surgery (MIS), aims to achieve
maximal therapeutic benefit with minimal tissue trauma, reduced blood loss, faster healing, and
improved cosmetic outcomes. This conceptual shift aligns deeply with Sushruta’s principles
emphasizing precision, minimal injury, gentle tissue handling, and doshic balance.
This review critically explores the relevance of Chedana, Bhedana, and Lekhana within MIS
practices such as laparoscopy, endoscopy, arthroscopy, laser surgery, and radio-frequency
ablative techniques. The article correlates surgical objectives, instruments, tissue handling,
postoperative recovery, and preventive strategies described by Sushruta with modern MIS
standards. Ayurvedic principles related to wound healing, asepsis, suture materials, and operative
ergonomics are also analyzed. The findings demonstrate that the foundational logic of MIS is
deeply rooted in Sushruta’s surgical wisdom.

Keywords: Trividha Shastra Karma, Chedana, Bhedana, Lekhana, Sushruta, Minimally Invasive Surgery, laparoscopic surgery, endoscopic surgery, Ayurvedic surgery.

Abstract: Childhood is a dynamic period marked by rapid physiological, immunological, and
metabolic development. Modern science identifies the gut microbiome as a crucial
determinant of these processes, influencing digestion, metabolism, neurodevelopment,
and immunity. Ayurveda, thousands of years earlier, described similar concepts through
Agni, Grahani, Koshtha, Stanya, and Bala. This review critically explores the
Ayurvedic interpretation of gut microbiome development, correlating classical
concepts with contemporary pediatric microbiology. The role of Agni maturation,
Grahani stabilization, Ahara, Panchakarma, Dinacharya, and Rasayana interventions
is highlighted in strengthening microbiome-mediated immunity in children. Clinical
implications for managing pediatric disorders such as recurrent infections, allergies,
malnutrition, and gastrointestinal dysbiosis are also discussed.

Keywords: Gut microbiome, Grahani, Agni maturation, Pediatric immunity, Ayurveda, Dysbiosis, Child health.

Abstract: Background:
Anxiety disorders, particularly Generalized Anxiety Disorder (GAD), represent one of the most
prevalent psychiatric conditions globally, significantly impacting quality of life and productivity.
The neuro-endocrine mechanisms underlying anxiety involve hyper-activation of the
hypothalamic–pituitary–adrenal (HPA) axis, cortisol exhaustion, and dysregulation of
neurotransmitters such as GABA and serotonin. Ayurveda describes anxiety in terms of
Chittodvega, a Manas vyadhi involving Vata-prakopa, Rajas-Tamas aggravation, and Oja-kshaya.
Shirodhara is traditionally indicated for disorders of mind and stress-related psychic disturbances.
Aim/Objectives:
To evaluate Shirodhara through modern neuro-hormonal mechanisms and classical Ayurvedic
principles in the management of anxiety disorders and GAD.
Methods:
A narrative review of Ayurvedic treatises (Bruhatrayee, Laghutrayee, Nighantu, Rasashastra
texts) and modern biomedical literature was conducted. Data were extracted from PubMed,
Scopus, Cochrane, and Google Scholar using keywords: Anxiety, GAD, Shirodhara,
neuroendocrine, cortisol, GABA, melatonin, HPA axis.
Key Review Findings: Shirodhara modulates HPA axis activity, decreases cortisol, enhances
GABA and serotonin levels, increases parasympathetic tone, and improves sleep architecture.
Ayurvedically, it pacifies Vata, balances Rajas-Tamas, nourishes Ojas, and stabilizes PranaVyana-Sadhaka Pitta.
Conclusion:
Shirodhara offers a promising integrative therapy for GAD through a dual framework neurohormonal regulation and Ayurvedic mind–body balancing. Further randomized, neurobiochemical studies are required for stronger clinical validation.

Keywords: Anxiety disorders, GAD, Shirodhara, HPA axis, cortisol, GABA, Manovaha srotas, Ayurveda, neuro-hormonal modulation, Rasayana therapy.

Abstract: Bal Panchakarma, a specialized branch of Ayurvedic pediatric purification therapy,
emphasizes gentle detoxification and strengthening of Agni and Dhatus in children
without disturbing their natural growth. In contrast, modern pediatric detoxification and
immunomodulatory therapies focus on removing metabolic toxins, supporting immune
homeostasis, and preventing chronic diseases. This article explores the physiological,
biochemical, and immunological correlations between Bal Panchakarma and modern
pediatric detoxification, highlighting the scientific rationale behind classical Ayurvedic
interventions such as Abhyanga, Swedana, Mridu Virechana, and Nasya. It also presents
evidence-based understanding of how these therapies modulate immunity, metabolism,
and detoxification at a molecular level.

Keywords: Bal Panchakarma, detoxification, immunomodulation, Agni, Dhatu poshana, Ayurveda, pediatrics.

Abstract: Seasonal purification or Rutucharya-based Shodhana is an integral concept of preventive
pediatrics in Ayurveda, aiming to balance Doshas and enhance overall health, growth,
and immunity in children. The concept emphasizes performing gentle detoxification
(Mridu Panchakarma) during specific seasons to harmonize the child’s physiology with
environmental transitions. This review explores the physiological basis, traditional
indications, and modern scientific correlations of Seasonal Shodhana in improving
pediatric health, metabolism, and growth outcomes. It also analyzes the evidence linking
Panchakarma with immunomodulation, detoxification, and metabolic homeostasis in the
growing child.

Keywords: Rutucharya, Mridu Panchakarma, pediatric health, growth, Dosha shamana, detoxification, Kaumarbhritya.

Abstract: Malnutrition continues to pose a significant global health challenge, particularly among
children, pregnant women, and the elderly. Ayurveda, with its holistic understanding of
the human body and nutrition, provides an insightful framework to combat malnutrition
through concepts such as Karshya (emaciation) and Dhatukshaya (tissue depletion). The
Ayurvedic approach emphasizes balanced nutrition, optimal digestive function (Agni), and
proper tissue formation (Dhatu poshana). This review explores the Ayurvedic
understanding of malnutrition in light of Karshya and Dhatukshaya, comparing it with
modern nutritional science. The study highlights the preventive, curative, and
rejuvenative measures including Ahara, Vihara, Rasayana, and Panchakarma
interventions that can contribute effectively to combating malnutrition.

Keywords: Malnutrition, Karshya, Dhatukshaya, Agnimandya, Rasayana, Ahara Vidhi, Ayurveda

Abstract: Childhood is a dynamic period marked by rapid physiological, immunological, and metabolic
development. Modern science identifies the gut microbiome as a crucial determinant of these
processes, influencing digestion, metabolism, neurodevelopment, and immunity. Ayurveda,
thousands of years earlier, described similar concepts through Agni, Grahani, Koshtha, Stanya,
and Bala. This review critically explores the Ayurvedic interpretation of gut microbiome
development, correlating classical concepts with contemporary pediatric microbiology. The role
of Agni maturation, Grahani stabilization, Ahara, Panchakarma, Dinacharya, and Rasayana
interventions is highlighted in strengthening microbiome-mediated immunity in children. Clinical
implications for managing pediatric disorders such as recurrent infections, allergies, malnutrition,
and gastrointestinal dysbiosis are also discussed.

Keywords: Gut microbiome, Grahani, Agni maturation, Pediatric immunity, Ayurveda, Dysbiosis, Child health

Abstract: Background:
Nighantus represent the advanced evolution of Ayurvedic Materia Medica, expanding beyond
Bruhatrayi with elaborate descriptions of dravya rasa–guna–veerya–vipaka–prabhava and
morphological identifiers. Several drugs recorded in Dhanvantari, Raja, Kaiyadeva, Madanpala,
and Bhavaprakasha Nighantu remain underutilized today despite historically documented
therapeutic potency (1)(2). Scientific pharmacognostic profiling enables revitalization of such rare
herbs through botanical authentication, quality assurance, and standardization.
Aim & Objectives:
1. To critically compile and analyse pharmacognostic traits of lesser-used Nighantu herbs.
2. To perform a comparative pharmacognostic evaluation of Haritaki fruits collected from
the Western Ghats, Himalayas, & Eastern India.
3. To correlate classical morphological descriptors with modern anatomical microscopy and
powder analysis.
Materials & Methods:
An Ayurvedic review was conducted using Nighantu databases, Bruhatrayi, Nighantu
commentaries, and modern pharmacognostic indexes. Microscopy of authenticated Haritaki
samples included TS, maceration, powder microscopy under normal & polarized light, and
histochemical staining using safranin–fast green dual mode (3)(4). Comparisons were made
based on stone cell clusters, vessel structure, epidermal cuticle, tannin localization, and rosette
crystals (5)(6).
Key Review Findings:
Parpat, Ajagandha, Surasa, Shyonaka, and Svadupami/Swaduparni demonstrate specific
micro-characters such as prismatic crystals, glandular trichomes, unicellular hairs, parenchymal
mucilage and porous pith that enable unambiguous authentication.
Haritaki samples varied significantly: Western Ghats fruits contained abundant stone cells and
tannin masses; Himalayan fruits showed thin pericarp and sparse trichomes; Eastern region
fruits had dense sclereids and high rosette crystal population (7)(8)(9).
These differences validate the Ayurvedic doctrine Desha-Bheda (regional variations) and
influence potency, stability, and formulation value.
Conclusion:
Pharmacognostic standardization bridges ancient textual ethnobotany with modern scientific
validation. Rare Nighantu herbs warrant reintegration into clinical practice after histological
authentication. Haritaki demonstrates strong geoclimatic phytovariation, necessitating sourcespecific monograph development for future pharmacopeial inclusion.

Keywords: Nighantu dravyas, Pharmacognosy, Haritaki microscopy, rare herbs, tannin content, Terminalia chebula, stone cells, histochemical analysis

Abstract: Regardless of your strength, body type, or health condition, yoga can reshape
the body and nurture the mind.. Yoga is an ancient art that originated in India about
6000 years ago. Earlier people used to practice yoga and meditation in their daily lives
because the impact of yoga on life is multidimensional that helps to boost physical,
mental and spiritual wellbeing. However, in today’s crowded and busy environment the
practice of daily yoga is getting diminished. The act of yoga consists of many poses
known as asanas that have different physical benefits. Bhujangasana is one among
such asanas. Bhujangasana gets its name from the Sanskrit term ‘bhujanga,’ meaning
‘snake’ or ‘serpent,’ and ‘asana,’ which translates to ‘posture.’ Thus, it is referred to as
cobra pose as it appears like the poster of a cobra with hood raised. Bhujangasana is
originally described in the ‘Gheranda Samhita,’ recognized as one of the three major
Hatha Yoga texts from the 17th century.The second chapter of this text portrayed 23
asanas for strengthening the body. Bhujangasana being one amongst them. It helps to
stretch muscles in the chest, shoulder and abdominal area. It helps to tone the
abdomen and strengthen the spine and most important it also helps to improve blood
circulation. It is a complete asana that strengthens both the spiritual and physical
health. It has a beneficial effect on the back and improves digestion at the same time.
Also, it helps to regulate the menstrual cycle.
Objectives: The objective is to extensively explore the benefits of yoga and specifically
Bhujangasana. Data source: All the available information related to Bhujangasana and
Yoga in classical texts like Charak Samhita Gherand samhita and its related
contemporaries, articles, journals.
Review methods: The information related to yoga and Bhujangasana and its benefits
are reviewed by comparing an analysing the different aspects of both classical texts and
contemporaries as well as contemporary authors. Conclusion: Bhujangasana is a
complete asana that strengthens both the spiritual and physical well-being.

Abstract: Acharya Charaka describes Sannipatodara as a type of Udara
classified under the Ashtamahagada, indicating its complex and difficultto-cure nature. The pathogenesis of Udara begins with impaired digestive
strength (Agnidosha), leading to improper nutrient assimilation
(Malavriddhi) and accumulation of waste products. Stagnation of these
wastes contributes to disease manifestation. Suppression of Agni along
with continued intake of causative factors (Hetu Sevana) results in the
production and accumulation of Ama, which vitiates Prana, Agni, and
Apana, causing obstruction in both upward and downward channels of circulation.
This overall imbalance leads to vitiation and excessive provocation of Vata.
Due to chronicity and severity caused by prolonged consumption of causative factors,
accumulation of Mala, and toxins, the disease may become irreversible. When Vata
Dosha dominates, overall body metabolism is disrupted, predisposing the patient to
serious complications such as hepatic failure, hepato-renal syndrome, muscle wasting,
hyperammonemia, and hepatic encephalopathy.
From a modern medical perspective, the pathogenesis of hepatic encephalopathy is
multifactorial, with elevated blood ammonia considered a key risk factor. Ammonia
produced during normal protein metabolism in the colon reaches systemic circulation
and accumulates in the central nervous system when liver detoxification is impaired.
To address this pathophysiological chain, Shahastravedhi Tarun Sneha has been
selected as a therapeutic intervention. Chronic alcohol consumption directly
contributes to hepatotoxicity, leading to alcoholic hepatitis and progression to liver
cirrhosis. In advanced cirrhosis, gut-derived neurotoxins bypass the liver due to
vascular shunting and reduced hepatic mass, reaching the brain and exacerbating
encephalopathy.
Ammonia detoxification primarily occurs in the liver and striated muscles. In patients with advanced
liver disease, significant muscle wasting is common, which Ayurveda correlates with the dominance
of Vata. The probable mode of action of Hingu Misrit Eranda Sneha is discussed in the current study
as a potential therapeutic approach for managing such complications.

Keywords: Udara, Mahagad, Hingu, Eranda Sneha

Abstract: Yoga is thus described as comprising a rich treasure of physical and mental
techniques that can be effectively used to create physical and mental wellbeing. Since its
introduction into modern culture, yoga has enjoyed a tremendous growth in popularity as
an healthy living. Yoga conceptualizes the human being as a multi layered, conscious
being, possessing three bodies or Sharira (Sthula-gross, Sukshma -subtle and Karana -
causal) and having a five layered existence (Pancha koshas), consisting of our anatomical,
physiological, psychological, intellectual and universal existential layers. Development of
an integrated self and a sound personality requires awakening and balancing of all these
five layers and treating the imbalances in the correct way by using different modalities of
treatment mentioned in Yoga and Ayurveda. This is a conceptual review to understand and
integrate different modalities of treatment on the basis of pancha kosha concept.

Keywords: Yoga, Panch Kosha, Mind, Treatment

Abstract: Ayurveda is only medical science which is known as science of life (Ayu). The
concept of
hitaayu, ahitaayu, sukhaayu and dukhaayu refers its unique wholesome approach for
healthy
life of a personIty focuses not only personal physical health but also gives more
emphasis on mental health. Caraka Samhita covers all the aspects of life like personal
(both
physical and mental values), social, occupational, emotional, and spiritual values with its
principles of ahaar, vihaar, achaar, indriyopkramniya and sadvritta. It describes a general
healthy and universal outlook especially for mental health with the help of its
philosophical approach of both mind and body. This article assembles basic principles of
Caraka Samhita related to Ayurvedic psychiatry. There is description about Basic
principles of Caraka Samhita related to maintain normal state of mental health as well as
categorization of mental symptoms of DSM IV-TR according to eight vibhramas.

Keywords: Ayurvedic psychiatry, Principles, mental faculties, eight vibramas.

Abstract: In Ayurveda Acharaya Shusrut mentioned Shwasa roga is mainly caused by
the Vata and Kapha doshas. Shwasa is broadly classified into five types i.e. Maha
shwasa, Urdhawa shwasa, Chinna shwasa, Kshudra shwasa, Tamaka shwasa. In modern
Tamak shwasa is co-related to Bronchial Asthma in which the lungs are filled with a fluid
called shleshmaka kapha, which is responsible for proper respiration, causes obstruction
of air way or respiratory tract especially the trachea. The aim to assess the prevalence
and characteristics of asthma by the Dietics, patha –apathya and Yogasana. Acharya
Charaka mentions the word pathya also as synonym of chikitsa (Ch. Chi 1/3). When
consumed in appropriate timing and quantity, Pathya Ahara and Yogasana can aid in
recovery from disease, either independently or alongside other medications. The Pathya
and Apathya are effective tools in Ayurveda for diagnosis as well as management of
diseases.
This paper intends to highlight on Ayurvedic dietics and Yogasana for prevalenting
Tamak Shwasa in contemporary time on the basis of Principles of Swasthavritta.

Keywords: Tamak shwasa,Pathya,Apathya,Yogasana,Ayurveda.

Abstract: Ayurveda is regarded as a timeless and comprehensive
science of health, as it emphasizes both the promotion of well-being
and the treatment of disease. In Ayurveda, urinary stones are
described under the term 'Mutrashmari,' where 'Mutra' means urine and
'Ashmari' means stone Mutrashmari the disease of Mutravaha strotas .
Acharya Sustruta described it as one of the ashta mahagadas.Acharya
Charaka mentioned Ashmari as one of Bastimarmashritha Vyadhi.
In Ayurveda various conservative medicine are mentioned for the
management of Mutrashamari with less side effect and minimum
recurrence of stone formation .In this case report pt visited OPD with
complaint of Mutradaha ,Adhaman,Sakashtamutrapravruti .The patient
was treated with Shaman Chikitsa Varunadi kwatha , Pashanbheda
Churna, Gokshur churna, Punarnava churna, Hriberpishti, Yavkshar
churna .
At the end of treatment patient got relief in signs and symptoms and USG
reports showed no evidence calculi in kidney.Details of USG mention
below in tubular form.Ayurvedic management offers a good approach to
manage mutrashmari .

Keywords: Mutrashmari ,Varunadi kwath , Pashanbheda ,Gokshur, Punarnava churna , Yavakshar churna,Hriberpishti .

Abstract: Acharya charak described Sannipatodara as one of the type of udara,
belongs to ashtomahagada, so it's difficult to cure. Udara Samprapti starts from
defective digestion strength i. e. Agnidosha & causes malavruddhi & its accumulation.
Increase in waste products and its stagnation are the reasons for the disease like
Udara, Suppression of Agni & continuation of hetu sevana leads to Ama production &
its accumulations, it vitiates prana, agni & apana due to which, there is obstruction to
upward & downward channel of circulation. Overall, it causes vitiation & excessive
provocation of vayu.
Considering, its chronicity & severity due to excessive consumption of hetus, excessive
accumulation of mala & toxins, the disease becomes irreversible. When Vata dosha
becomes dominant, it disrupts overall body metabolism, making the patient susceptible
to complications such as hepatic failure, hepato-renal syndrome, muscle wasting,
hyperammonemia, and encephalopathy.. The pathogenesis of hepatic encephlopathy
is multi-factorial & ammonia is considered as an important risk factor. As per Modern
science, elevation in Blood Ammonia causes hepatic encephalopathy ammonia
reaches the systemic circulation & accmulates in the central nervous system, to
combact this chain of pathogenesis, we have selected "Shahastravedhi
Tarun Sneha." Alcohol is direct hepato-toxic and will develope alcoholic
hepatitis & further it will progress to liver cirrhosis. As the disease
becomes advanced, serious complications of cirrhosis occurs. In liver
cirrhosis, gut derived neuro-toxins that are not removed by the liver,because of vascular shunting and decrease hepatic mass gets to the brain. Ammonia is
produced during normal protein metabolism in the colon. liver & striated muscles plays a
major role in de-toxification of ammonia. Patients with advanced liver disease typically
have significant muscle wasting & muscle wasting is common occurance in liver cirrhosis
due to dominance of Vayu.Probable mode of action of Hingu misrit Erand sneh is
described in current paper

Keywords: Udar,Mahagad, Hingu, Erand sneh

Abstract: In 21s t century with continuous changing life style environment and dietary
habits have made man the victim of many diseases. Osteoarthritis is one of them. It
hampers the day-to-day activities of life due to increase in pain and stiffness in the
joint. As age progresses the degenerative changes increases with simultaneously
aggravate the disease. In chronic condition the pain is unbearable and degenerative
changes are irreversible. Keeping in view, this burning problem of present era and its
devastating effect it was decided to conduct study on osteoarthritis with Ayurvedic
principle of Abhyantar tailpaan(Internal application as Snehapana) is effective in
Sandhivata, Sneha Dravya possesses Drava, Sukshma, Sara, Snigdha, Manda,
Mrudu, Guru properties which are just opposite to those of Vata so it alleviates Vata. In
its balanced state, Vayu helps maintain harmony between the Doshas and Dhatus. It
is stated that by the regular use of snehapana, degenerative changes of old age
could be prevented and cured. This anti-ageing effect of snehapana is very important
as far as Sandhivata is concerned. It restores depleted Dhatus and enhances Prana
(vital energy) while also strengthening Agni.

Keywords: Snehapana, Sandhivata

Abstract: In recent years many studies and researches conducted all across the world
proved that yoga is useful in the physical, mental, social and spiritual wellbeing. In
today’s world a huge crowd of student appearing for competitive exam. The students
entering new academic and competitive world experience higher academic work load and
family expectations. Due to their immaturity and uncertainty that they seem not to have
any control over the situation.The study involved 50 first-year MBBS students to assess
the effects of yogic practices on anxiety levels during routine activities before
examinations. The result of the indicated a statistically significant reduction in not only the
number of failures but also in the anxiety level of student. With reference to this the
Indian Government should keep the special practice hours for yoga and pranayama from
the school itself. This will not only maintain the physical, mental, social wellbeing of the
school going student but also prepare their mind for accepting the new challenges and
managing stress for future

Abstract: Background
Deviated Nasal Septum (DNS) is a structural disorder leading to nasal obstruction, mouth
breathing, snoring and recurrent sinusitis. Modern management focuses on septoplasty, whereas
Ayurveda describes conservative nasal therapies such as Nasya, Dhoomapana and Swedana
which help in relieving obstruction and improving mucosal patency [1,2].
Objective
To evaluate DNS through an Ayurvedic conceptual framework and highlight conservative
management strategies.
Methods
Classical references from Charaka Samhita, Sushruta Samhita, Ashtanga Hridaya, Kashyapa
Samhita, Nighantus were reviewed along with modern ENT literature and clinical studies [1–14].

Keywords: DNS, Nasa Pratinaha, Nasagata Vata, Nasya, Dhoomapana, conservative Ayurvedic ENT management.

Abstract: Background:
Benign Prostatic Hyperplasia (BPH) is a progressive, age-related condition
characterized by non-malignant enlargement of the prostate, lower urinary tract
symptoms (LUTS), and reduced quality of life among ageing men. Conventional
therapy—α-blockers, 5-α-reductase inhibitors, and surgical interventions—often leads
to adverse effects or incomplete symptom relief. Ayurveda conceptualizes BPH under
Mutraghata, Vatashtheela, and Mutra-krichchhra, emphasizing Vata-dushti, Srotorodha,
and Meda/Mutravaha Srotas dysfunction. Integrative approaches combining
Panchakarma, Rasayana, and herbal formulations show potential for symptom relief
and disease modification.
Methods:
A narrative review was conducted using PubMed, Scopus, AYUSH Research Portal,
IndMED, and Google Scholar. Search terms included “Benign Prostatic Hyperplasia,”
“Ayurveda,” “Mutraghata,” “Gokshura,” “Varuna,” “Panchakarma,” and “prostate
inflammation” using Boolean operators (AND/OR). Literature published between 1980–
2024 was included. Clinical trials, observational studies, conceptual papers,
mechanistic studies, and classical Ayurvedic texts (Charaka Samhita, Sushruta
Samhita, Ashtanga Hridaya) were evaluated. PRISMA principles guided screening and
selection. Exclusion criteria were non-peer-reviewed papers, incomplete data, and nonhuman studies unless mechanistic insights were relevant.
Results:
Ayurvedic descriptions of Mutraghata, Vatashtheela, and Mutra-krichchhra share
symptomatic overlap with BPH. Herbs such as Gokshura, Punarnava, Varuna, Kanya,
and formulations like Chandraprabha Vati, Gokshuradi Guggulu, Punarnavadi Kashaya,
and Shilajit Rasayana exhibit anti-inflammatory, diuretic, anti-androgenic, and antiproliferative effects. Clinical studies demonstrate reductions in IPSS scores, prostate
size, and post-void residual urine. Panchakarma therapies like Uttara Basti, Matra
Basti, and Virechana show improvements in urinary flow and symptom burden.
Research gaps include heterogeneity in methodologies, small sample sizes, and lack of
long-term outcome data.
Conclusion:
Integrative Ayurvedic management shows promising potential in alleviating LUTS,
reducing inflammation, and improving quality of life in BPH. Herbal and Panchakarmabased interventions may serve as adjunct or complementary therapies. Future research
should focus on multicentric RCTs, standardized formulations, and mechanistic studies
to evaluate long-term disease modification.

Keywords: Benign Prostatic Hyperplasia, BPH, Lower Urinary Tract Symptoms, LUTS, Ayurveda, Mutraghata, Vatashtheela, Gokshura, Varuna, Punarnava, Chandraprabha Vati, Gokshuradi Guggulu, Panchakarma, Basti, Uttara Basti, Virechana, Integrative Medicine, Rasayana, Prostate Health.