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Authors / Members: Dr. Anil Ganeshrao Ghandge1*, Dr. Uday Bhikanrao Bhoir2 , Dr. Ashishkumar Laxmanrao Bansod3 .

Abstract: Marma Sharir describes 107 vital anatomical loci where trauma produces severe functional impairment or mortality. Classical Ayurvedic literature attributes these sites to the confluence of mamsa, sira, snayu, asthi, and sandhi structures (1). Contemporary anatomical investigations suggest that these correspond to major neurovascular complexes (2,3). Objective: To systematically evaluate classical descriptions of marma and correlate them with modern neurovascular anatomy.Methods:A systematic review was conducted following PRISMA 2020 guidelines (4). Databases including PubMed, Scopus, Web of Science, Google Scholar, and AYUSH Research Portal were searched up to December 2025. Classical Ayurvedic texts were reviewed for textual references. Studies correlating marma with anatomical neurovascular structures were included. Results: Forty-eight studies met inclusion criteria. Strong correlations were observed between Sira marma and arterial trunks (5,6), Snayu marma with peripheral nerve plexuses (7), and thoracic marma with cardiac and autonomic plexuses (8,9). Conclusion: Classical marma descriptions show significant convergence with modern neurovascular anatomy. Integrative anatomical mapping may enhance trauma assessment and surgical safety.

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