Panchakarma and Non-Communicable Diseases (NCDs): A Comprehensive Integrative Review
Abstract
Acharya charak described Sannipatodara as one of the type of udara,
belongs to ashtomahagada, so it's difficult to cure. Udara Samprapti starts from
defective digestion strength i. e. Agnidosha & causes malavruddhi & its accumulation.
Increase in waste products and its stagnation are the reasons for the disease like
Udara, Suppression of Agni & continuation of hetu sevana leads to Ama production &
its accumulations, it vitiates prana, agni & apana due to which, there is obstruction to
upward & downward channel of circulation. Overall, it causes vitiation & excessive
provocation of vayu.
Considering, its chronicity & severity due to excessive consumption of hetus, excessive
accumulation of mala & toxins, the disease becomes irreversible. When Vata dosha
becomes dominant, it disrupts overall body metabolism, making the patient susceptible
to complications such as hepatic failure, hepato-renal syndrome, muscle wasting,
hyperammonemia, and encephalopathy.. The pathogenesis of hepatic encephlopathy
is multi-factorial & ammonia is considered as an important risk factor. As per Modern
science, elevation in Blood Ammonia causes hepatic encephalopathy ammonia
reaches the systemic circulation & accmulates in the central nervous system, to
combact this chain of pathogenesis, we have selected "Shahastravedhi
Tarun Sneha." Alcohol is direct hepato-toxic and will develope alcoholic
hepatitis & further it will progress to liver cirrhosis. As the disease
becomes advanced, serious complications of cirrhosis occurs. In liver
cirrhosis, gut derived neuro-toxins that are not removed by the liver,because of vascular shunting and decrease hepatic mass gets to the brain. Ammonia is
produced during normal protein metabolism in the colon. liver & striated muscles plays a
major role in de-toxification of ammonia. Patients with advanced liver disease typically
have significant muscle wasting & muscle wasting is common occurance in liver cirrhosis
due to dominance of Vayu.Probable mode of action of Hingu misrit Erand sneh is
described in current paper
Keywords
Udar,Mahagad, Hingu, Erand sneh