Abstract

Background Recurrent Implantation Failure (RIF) is a distressing condition encountered in assisted reproductive technology (ART), characterized by repeated failure of embryo implantation despite transfer of good-quality embryos. It reflects a complex interplay of endometrial receptivity defects, immune dysregulation, hormonal imbalance, thrombophilia, and psychosomatic stress. Ayurveda, though not explicitly describing RIF, offers a comprehensive framework through concepts such as Vandhyatva, Garbhasambhava Asambhava, Kshetra Dushti, Artava Dushti, and Beeja Dosha. Objective To critically analyse Recurrent Implantation Failure through Ayurvedic principles, correlate it with modern reproductive science, and review Ayurvedic therapeutic strategies for improving implantation and pregnancy outcomes. Methods A narrative review was conducted using classical Ayurvedic texts (Charaka, Sushruta, Ashtanga Hridaya, Kashyapa Samhita), commentaries, and Nighantus, along with modern scientific databases (PubMed, Google Scholar, DHARA, AYUSH Research Portal). Conceptual analysis and integrative interpretation were employed. Results Ayurvedic concepts such as Kshetra Shuddhi, Artava Prasadana, Vata Shamana, Rasa–Rakta– Artava Poshan, and Rasayana directly influence implantation success. Panchakarma procedures like Basti, Nasya, Uttara Basti, and internal medications including Phala Ghrita, Ashwagandha, Shatavari, Guduchi, and Lodhra demonstrate potential in improving endometrial receptivity, hormonal balance, immune tolerance, and uterine environment. Integrative Ayurvedic intervention may reduce repeated ART failures. Conclusion Ayurveda provides a holistic and individualized approach to RIF by correcting systemic imbalances, enhancing uterine receptivity, and addressing psychological stress. Integrative management combining ART with evidence-based Ayurvedic therapies may improve implantation rates and reproductive outcomes.